Manchester United remain without long-term absentee Lisandro Martinez.
Matthijs de Ligt was also missing from their Europa League final squad, but Leny Yoro, Diogo Dalot and Joshua Zirkzee all returned to action in Bilbao.
Jacob Ramsey is available after suspension for Aston Villa but loanee Marcus Rashford is ineligible to face his parent club and has missed recent games through injury anyway.
Villa’s player of the season Youri Tielemans returned to training on Friday and could be involved after a two-match absence with a calf issue.
